Multiple Sclerosis

Medically reviewed by Dr. Kimberly Langdon Cull, M.D. on August 5, 2023 This study found that patients with multiple sclerosis and neuromyelitis optica spectrum disorder have an increased risk of all forms of dementia. Both neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) patients exhibit cognitive impairment; however, the risk of dementia in these...

Somite and neurite density imaging is a novel high-grade MRI approach that is effective for determining cellular changes occurring in the gray matter and cortex in brain tissue of multiple sclerosis patients compared to brain tissue of healthy individuals, which can help identify disability status in multiple sclerosis patients. Multiple sclerosis (MS) is associated with...

This experimental study of the tear fluid proteome demonstrated that the proteins found in the tear fluid of multiple sclerosis patients are modified and may indicate inflammation, which can be helpful in the diagnosis and treatment of these patients. Multiple sclerosis (MS) is a neurodegenerative condition that involves the central nervous system (CNS). The diagnostic...

Utilizing an eye-tracking system for bed positioning based on eye movements is a viable and dependable option for individuals experiencing advanced stages of multiple sclerosis.  Individuals with advanced multiple sclerosis (MS) who exhibit limited motor abilities must have frequent position changes to prevent further complications. A newly published study describes the development and utility of...

Apigenin exerts its inflammatory properties by mediating the inhibition of the proliferation of interferon gamma-secreting Th1 cells. The acetylated version of apigenin-3-acetate exhibits comparative immunomodulatory outcomes compared to methyl-prednisolone-acetate and apigenin. Despite advancements in the treatment modalities for multiple sclerosis (MS), the associated morbidity remains high. A study published in Cell Journal evaluated the immunomodulatory...

This study presents a review of the influence of different environmental factors on autoimmune diseases. The interplay between environmental factors and genetic susceptibility triggers autoimmune disease onset. Risk factors such as Epstein–Barr virus infection and coffee, tobacco, and alcohol consumption have been extensively reviewed. A review in the journal Frontiers in Immunology has focused on...

This article reviews treatments for the rehabilitation of multiple sclerosis patients. Multiple sclerosis (MS) is an autoimmune inflammatory disorder that causes demyelination in the central nervous system. Progression of the disease leads to chronic neurological deficits. Professional rehabilitation therapy during the disease course can reduce disability and improve the functional status of MS patients. A...

This study presents a review of the neurogenerative mechanisms in multiple sclerosis. Multiple sclerosis (MS) is an autoimmune, inflammatory, and neurodegenerative disease of the central nervous system (CNS). The hallmark of MS is inflammatory demyelinating lesions, impaired recovery of which may lead to permanent neurodegeneration and disability. A study in the journal WIREs Mechanisms of...

Multiple sclerosis and neuromyelitis optica spectrum disorder exhibit significant differences in optical coherence tomography, with the latter being associated with significant thinning of the ganglion cell layer during both acute episodes and episodes at 6 months. The thickness of different retinal layers can be measured by a non-invasive tool known as optical coherence tomography (OCT)....