Condition Center

A successful transition from pediatric to adult care is crucial for adolescents and young adults (AYAs) living with sickle cell disease. Preparation for this transition is key to reducing the morbidity and mortality risks they could potentially face later in life. Researchers at the University of Missouri conducted a cross-sectional, correlational study to explore the...

It is considered best practice for kids with sickle cell anemia to receive antibiotic prophylaxis to prevent serious infections. Additionally, it is recommended that they undergo transcranial Doppler (TCD) screening to determine their risk of overt stroke. However, it remains unclear how many children with sickle cell anemia actually receive antibiotic prophylaxis and/or undergo TCD...

This study, published in the Journal of Pharmacology and Experimental Therapeutics, evaluates the response of both non-human primates and healthy human subjects to etavopivat. Etavopivat is a small molecule activator of the glycolytic enzyme erythrocyte pyruvate kinase. It is being developed to treat sickle cell disease (SCD) and is hypothesized to work via multiple mechanisms that increase...

Before the pandemic, Ohio offered in-person education for parents of children with sickle cell trait (SCT), a condition that afflicts about 8% of African Americans born each year. It was found that participating individuals with a low health literacy rate were less likely to achieve a suitable level of knowledge about managing SCT. This study,...

Many pediatric patients with sickle cell disease (SCD) struggle with neurocognitive and academic difficulties and do not receive proper educational and therapeutic support for these issues. As a result, it is vital that these patients are identified and referred for appropriate care. This article, published in Clinical Practice in Pediatric Psychology, analyzes referrals made in a...

Sickle Cell Disease (SCD) crisis prevention and management are crucial yet challenging, as pain crises can happen at any instance and require immediate attention. In addition, caregivers of patients with SCD bear a great deal of responsibility. Caregiving responsibilities frequently come at a high psychosocial cost and necessitate significant lifestyle modifications. The prevalence of emotional...

Cancer death rates higher for Black versus White males and females; kidney cancer death rates higher for AI/AN people There are still considerable racial/ethnic and sociodemographic disparities in cancer occurrence and death rates, according to a report published online Dec. 8 in CA: A Cancer Journal for Clinicians. Farhad Islami, M.D., Ph.D., from the American...

Risk for hypertension even higher for those receiving left-sided radiation therapy, endocrine therapy Women with, versus without, a history of breast cancer have a higher incidence of hypertension and diabetes up to 10 years following diagnosis, according to a study published online Jan. 13 in the Journal of Clinical Oncology. Marilyn L. Kwan, Ph.D., from...

A new analysis uncovers a racial paradox in prostate cancer care: While Black men are often diagnosed later and with more aggressive disease than white men, radiation therapy seems to work better for them than for their white peers. To come to that conclusion, researchers reviewed seven trials comprising more than 8,800 men with prostate...