OBGYN & Women’s Health

Sickle cell disease is known to be associated with worse pregnancy outcomes and higher maternal mortality. However, a new study shows that racial disparities significantly contribute to adverse pregnancy outcomes in Black women. Sickle cell disease (SCD) is more likely to affect people of African descent. Additionally, it is known that SCD significantly increases the...

Medically reviewed by Dr. Kimberly Langdon Cull, M.D. on Sept. 22, 2023 Dolutegravir produces more frequent viral suppression during delivery than current antiretroviral therapy regimens, including raltegravir and atazanavir-ritonavir. The medical literature contains limited data on the safety and efficacy of dolutegravir antiretroviral therapy (ART) versus current therapy regimens for managing human immunodeficiency virus type 1...

Medically reviewed by Dr. Kimberly Langdon Cull, M.D. on Sept. 22, 2023 Increased expression of hypoxia-inducible factor and altered expression of its dependent genes orchestrate the development of uterine fibroids. The pathways implicated in the development of uterine fibroids include proliferation, vessel morphogenesis, cell growth, adhesion, metabolic changes, migration, and myoblast differentiation. Uterine fibroids are benign...

Medically reviewed by Dr. Kimberly Langdon Cull, M.D. on Sept. 22, 2023 A combined model of T2-weighted imaging radiomics and clinical imaging features was effective for predicting the risk of reintervention prior to high-intensity focused ultrasound ablation. Uterine fibroids are described as benign gynecological tumors that are treated by high-intensity focused ultrasound (HIFU) ablation, among other...

Medically reviewed by Dr. Kimberly Langdon Cull, M.D. on Sept. 22, 2023 Oxytocin and combined administration of tranexamic acid and ethamsylate did not yield any significant improvement in the management of intraoperative bleeding during abdominal myomectomy for uterine fibroids in this study. Myomectomy is the treatment of choice in the management of uterine fibroids; however, myomectomy-related...

Medically reviewed by Dr. Kimberly Langdon Cull, M.D. on Sept. 21, 2023 Chemoradiotherapy with concomitant nivolumab was found to be safe and effective for improving progression-free survival rates in cervical cancer. Concurrent chemoradiotherapy (CRT) improves immune-mediated tumor control by increasing phagocytosis and antigen presentation. The NiCOL phase I trial, conducted by Rodrigues et al., aimed to...

Possible higher risk of recurrence in association with drinking seen for women with lower body mass index. For women with breast cancer with higher body mass index (BMI), alcohol drinking is associated with a lower risk of overall mortality, according to a study published online Aug. 9 in Cancer. Marilyn L. Kwan, Ph.D., from Kaiser...

Medically reviewed by Dr. Shani S. Saks, D.O. on August 2, 2023 African-American Women have significantly higher pregnancy complication rates than White women. Maternal mortality rates among AAW are three times higher than for White women due to poor healthcare access, structural and medical racism, and resultant stresses. The presence of inflammatory bowel disease in...

To date, research efforts on excess postpartum weight retention have been largely focused at the individual level. Investigations are needed to determine the factors contributing to ethnic and racial disparities in postpartum weight retention.  Approximately 75% of people who give birth tend to exhibit postpartum weight retention, which is further associated with the risk of...