Cardiology

The apolipoprotein B/A1 ratio can be used to predict the amount of tissue prolapse seen on an optical coherence tomography scan, and it is linked to how easily the apolipoprotein B/A1 plaque can break, according to a recent single-center, cross-sectional analysis. The apolipoprotein (Apo) B/A1 ratio is considered a reliable predictor of atherosclerotic cardiovascular disease....

An analysis of cohort data from the Multi-Ethnic Study of Atherosclerosis database found that elevated remnant cholesterol is a residual risk factor for aortic valve calcium progression, regardless of the conventional cardiovascular risk factors. Aortic valve calcium (AVC) is associated with the development of calcific aortic valve disease, which is one of the leading causes...

First-trimester dyslipidemia in pregnant women with subclinical hypothyroidism is associated with an increased risk of adverse pregnancy outcomes, according to a recent cohort study. Subclinical hypothyroidism is associated with dyslipidemia and may have adverse pregnancy outcomes. This thyroid disorder is common during pregnancy, increasing the risk for small for gestational age infants, preterm birth, and...

High lipoprotein-associated phospholipase A2 activity is associated with an increased risk for cardiovascular death and major adverse cardiovascular events in patients undergoing maintenance hemodialysis, facilitating the identification of patients at a greater cardiovascular mortality risk, according to the results of a recent prospective cohort study. Dyslipidemia is a common complication among chronic kidney disease patients...

A new randomized clinical trial shows that pitavastatin or other statins may help reduce major cardiovascular events in those living with HIV. These benefits are not just due to LDL cholesterol reduction. HIV significantly increases atherosclerotic cardiovascular disease incidence in those living with HIV. Studies suggest that those living with HIV have twice the risk...

Initiators of statins aged 75 years or older had higher mean percentage reduction than those younger than 50 years. For older versus younger adults, low- to moderate-intensity statins are associated with a greater reduction in low-density lipoprotein cholesterol (LDL-C), according to a study published online Aug. 1 in the Annals of Internal Medicine. Giulia Corn, Ph.D.,...

Recent research analyzed the association of modifiable risk factors with cardiovascular disease and death in a global cohort. Modifiable risk factors such as body mass index (BMI), systolic blood pressure (SBP), non-high-density lipoprotein (non-HDL) cholesterol level, smoking, and diabetes are associated with cardiovascular disease (CVD); however, data regarding their impact varies according to the study...

Higher serum levels of low-density lipoprotein cholesterol are positively related to the risk of early-onset vasomotor symptoms in premenopausal women. The predominant symptoms evident during the menopausal transition are vasomotor symptoms, including night sweats and hot flashes. Long-lasting and severe vasomotor symptoms tend to be associated with obesity, adverse cholesterol levels, high blood pressure, and...

Those randomly assigned to receive ACE inhibitor had increased risks for stroke mortality, fatal and nonfatal hospitalized stroke versus diuretic group For patients with hypertension and at least one other coronary heart disease risk factor, cardiovascular disease (CVD) mortality is similar for those receiving a thiazide-type diuretic, calcium channel blocker (CCB), or angiotensin-converting enzyme (ACE)...