Cardiology

Menopausal symptoms may not be directly linked to cardiometabolic risk, nor do they appear to be a reliable predictor of how risk factors may change as menopause approaches. The menopausal phase brings about various symptoms, such as hot flashes and night sweats, aka vasomotor symptoms (VMS), as well as challenges with sleep, feelings of anxiety...

Promising new treatments for cardiac amyloidosis are expected in the near future. Cardiac amyloidosis (CA) results from the deposition of misfolded proteins in the cardiac tissue. Its two main forms are light chain amyloidosis (AL) and transthyretin amyloidosis (ATTR), further classified as familial (vATTR) and wild-type (wtATTR). The treatments for AL, wtATTR, and vATTR differ...

Knowledge of red flags suggesting cardiac transthyretin amyloidosis is crucial for identifying at-risk patients and establishing the correct diagnosis. Cardiac amyloidosis is caused by the extracellular deposition of misfolded proteins in cardiac tissue. Wild-type transthyretin amyloidosis (wtATTR) is the most common form of cardiac amyloidosis. It mostly affects elderly patients, who usually present with heart...

This study highlights the clinical characteristics and healthcare resource use of patients at higher risk for wild-type transthyretin amyloid cardiomyopathy identified using a machine learning model. Transthyretin amyloid cardiomyopathy (ATTR-CM) can lead to heart failure (HF). If there is a delay in the diagnosis of wild-type ATTRCM (ATTRwt-CM), patients may undergo multiple hospital visits before...

Benefits across stroke types seen in duration-dependent manner. Statin use is associated with a lower risk for incident stroke and transient ischemic attack (TIA) in a duration-dependent manner among patients with atrial fibrillation (AF), according to a study presented at the annual meeting of the European Heart Rhythm Association, held from April 16 to 18...

Risk seems to escalate in dose-response manner for frequency of mobile phone use.  Mobile phone use for making or receiving calls was significantly associated with a higher risk for new-onset hypertension, according to a study published online May 4 in the European Heart Journal: Digital Health. Ziliang Ye, from Southern Medical University in Guangzhou, China, and...

After elective percutaneous coronary intervention, prolonged bivalirudin infusion protects against procedural myocardial injury. Procedural myocardial injury (PMI) is common after elective percutaneous coronary intervention (ePCI) and is linked to an increased risk of subsequent adverse cardiac events. In the post-PCI period, PMI is characterized by an increase in cardiac troponin I (cTnI) levels above the...

The positive correlation of bile acid levels in biliary atresia to myocardial structural changes highlights their potential causative association with cardiomyopathy in these patients. Cirrhotic cardiomyopathy comprises pathologic cardiac structural and functional changes in cirrhotic patients. It has a prevalence of approximately 30% and is a major cause of morbidity and peri-operative mortality in these...

Negative association of hypertension and blood pressure change with regional brain volumes stronger in men than women. Hypertension and increasing blood pressure (BP) in early adulthood are associated with lower mean regional brain volumes and poorer white matter integrity in late life, according to a study published online April 3 in JAMA Network Open.  ...