June 7, 2021

Many barriers prevent patients with wet age-related macular degeneration (AMD) from adhering to their appointments. COVID-19 was a major barrier for many patients who did not want to risk leaving home for eye screening or follow-up appointments due to fear of catching the virus. Transportation is an especially challenging barrier for patients with wet AMD....

Of the two forms of age-related macular degeneration (AMD), non-neovascular (dry) AMD and neovascular (wet) AMD, 90% of all AMD cases are classified as dry, meaning the macula’s light-sensitive cells slowly deteriorate. Cases of wet AMD are less common (10%) but more severe. Wet AMD is advanced AMD that can cause legal blindness in patients,...

Anti-vascular endothelial growth factor therapy, or anti-VEGF therapy, has become one of the most useful and effective therapies for wet age-related macular degeneration (AMD). This retrospective cohort study focuses on racial/ethnic differences in anti-VEGF intravitreal injection treatment. The 104,430 patients studied were commercially insured and had wet AMD, among other conditions. Main outcomes included receiving...

Choroidal neovascularization (CNV) refers to the growth of blood vessels that break into the subretinal pigment epithelium. It is a major cause of vision loss and is associated with wet age-related macular degeneration (AMD). This study sought to analyze novel biomarkers and gene expression signatures of AMD and focuses on the EFEMP1 gene. The researchers...

Convolutional neural networks (CNN) are a type of deep learning neural network that is most often used to evaluate visual imagery. Detection of Apoptosing Retinal Cells (DARC) is a technique that uses laser ophthalmoscopy to create images of the retina. This study focuses on using a CNN DARC algorithm to predict subretinal fluid formation in...