Condition Center

A randomized controlled trial found that nomograms based on multiple Cox regression models could effectively predict the risk factors associated with overall survival and cancer-specific survival in patients with localized prostate cancer as well as assess survival differences between surgery and radiotherapy.  Prostate cancer affects a substantial proportion of men across the globe, with more...

A nurse-led mobile-based health coaching program promoted positive lifestyle changes that improved various parameters of metabolic syndrome in prostate cancer patients. Prostate cancer patients are prone to adverse metabolic changes that stem from the physical effects of androgen deprivation therapy (ADT). These changes include body fat accumulation and abnormal fasting glucose levels, with subsequent development...

A retrospective cohort study finds that multimodal radiomics and pathomics based on deep learning algorithms are useful tools for predicting the risk of bone metastases in patients diagnosed with primary prostate cancer. Bone metastasis is a common consequence of disease progression in primary prostate cancer patients and plays an important role in the morbidity and...

Secondary analysis of a prospective trial finds that while repeated screening for prostate cancer is crucial to the detection of pathology, the proportion of magnetic resonance imaging scans that prompt suspicion of cancer is relatively low. Prostate cancer screening with prostate-specific antigen (PSA) plays a pivotal role in decreasing cancer-related mortality. Screening with PSA testing...

A newly published phase 2 study finds that the antitumor effect of AZD4635 with durvalumab or oleclumab is minimal in pretreated metastatic castration-resistant prostate cancer, with the treatment regimen being well-tolerated and generally safe. Metastatic castration-resistant prostate cancer (mCRPC) has a poor prognosis and limited overall survival rates. The standard treatment for mCRPC patients comprises...

Multiple sclerosis treatment with interferon beta may infrequently cause thrombotic microangiopathy, resulting in acute kidney injury. However, a newly published literature review finds that early identification of the complication and treatment with eculizumab may help prevent end-stage renal disease. Multiple sclerosis (MS) is a prevalent inflammatory demyelinating disorder of the central nervous system, mostly affecting...

A cohort study found glial fibrillary acid protein may be a reliable cerebrospinal fluid biomarker for differentiating progressive multiple sclerosis from relapsing disease. Multiple sclerosis (MS) presents a complex challenge in clinical management due to its varied progression patterns and the absence of precise biological markers to predict disease course. Two MS types, relapsing and...

A systemic review and meta-analysis found that natalizumab was similarly effective in both standard and extended interval dosing. However, the study also found that extended interval dosing did not improve its safety profile. Multiple sclerosis (MS) is a chronic immune-mediated central nervous system (CNS) disease with poorly understood pathology. However, it is known that immune...

Findings seen among poor surgical candidates, with recurrence risk of 10 percent seen at 16 months Cryoablation can be performed effectively in nonsurgical breast cancer patients with varying tumors, according to a study presented at the annual meeting of the Society of Interventional Radiology, held from March 23 to 28 in Salt Lake City. Jolie...