Condition Center

Ruxolitinib cream monotherapy rapidly and significantly improves signs and symptoms of atopic dermatitis such as inflammatory skin lesions and itch reduction, in all areas of the body, according to pooled results of two phase 3 studies. Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by intense itching and redness, particularly in visible areas...

By Roger Mosley The real-life effectiveness and safety of dupilumab in treating moderate-to-severe atopic dermatitis was explored in a recent retrospective study on patients with various comorbidities, including malignancies. The drug may be safe and effective across a diverse patient demographic, reinforcing its potential as a versatile treatment option in clinical practice. Dupilumab proved effective...

Low-dose acetylsalicylic acid reduces inflammatory protein levels and tissue perfusion in dense breast tissue in postmenopausal women, according to the results of a new phase II clinical trial. High mammographic density is a major risk factor for breast cancer, contributing to approximately 30% of all breast cancer. There is a lack of research regarding the...

DRL-Trastuzumab was found to have similar efficacy, safety, pharmacokinetics, and immunogenicity as Herceptin in HER2-positive breast cancer patients in a randomized, double-blind study. Trastuzumab, marketed under the brand name Herceptin, is a standard therapy for human epidermal growth factor receptor 2 (HER2)-positive breast cancer. The drug DRL_TZ, a potential trastuzumab biosimilar to Herceptin, was developed...

Studies show that quantitative and qualitative alterations in the skin population of C. Acnes is associated with higher atopic dermatitis risk, according to the results of a new literature review. Cutibacterium acnes plays an opportunistic role in acne vulgaris. However, it is also a commensal bacteria that plays an important role in maintaining skin health,...

by Roger Mosley A retrospective cohort study analyzing a large dataset found that atopic dermatitis is associated with a significant increase in the risk of various skin cancer types. Atopic dermatitis (AD) causes scaly, itchy patches and is relatively benign. Although its pathogenesis is not fully understood, it is known that disruption in skin barrier...

A recent case series reports significant symptom improvement in periorbital atopic dermatitis symptoms with the use of tacrolimus ointment, with minimal side effects. This approach marks a notable advancement in dermatological and ophthalmological care, offering a promising alternative to traditional steroid treatments. Tacrolimus ointment shows promising outcomes in treating periorbital atopic dermatitis with minimal adverse...

Hyperspectral imaging emerges as a potential tool in diagnosing erythema severity within atopic dermatitis, offering improved accuracy over traditional visual assessments. This innovative approach could improve objectivity and efficiency in skin inflammation evaluation. Hyperspectral imaging offers a detailed evaluation of erythema, surpassing traditional visual assessments. This study compared the efficacy of hyperspectral imaging against conventional...

Significant health literacy limitations may exist among atopic dermatitis patients, highlighting the need for tailored healthcare communication and support. A cross-sectional study associates limited health literacy with poorer health-related quality of life and older age, suggesting potential ways to improve patient care. Nearly one-third of atopic dermatitis patients exhibit limited health literacy, impacting their ability...