Dementia

Small improvement seen in global cognition scores, but no different from those following control diet with mild caloric restriction. The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) with mild caloric restriction does not change cognition or brain magnetic resonance imaging (MRI) outcomes compared with a control diet with mild caloric restriction, according to a study published...

As extreme heat continues to blanket numerous parts of the United States, Americans with dementia may be particularly challenged. “Triple-digit temperatures and heat indexes are especially dangerous for someone with a dementia-related illness such as Alzheimer’s disease, because the effects of dementia can impair their ability to notice if they are developing heat stroke or...

Women with atrial fibrillation and normal baseline cognition had higher risk of disease progression from normal to MCI, MCI to dementia Atrial fibrillation (AF) is associated with increased odds of and with more rapid progression to mild cognitive impairment (MCI) and dementia among women versus men, according to a study published online June 23 in Alzheimer’s...

Greater effect seen for patients aged 70 years and older at time of bacillus Calmette-Guerin vaccination. The bacillus Calmette-Guerin (BCG) vaccine is associated with a significantly lower rate and risk for Alzheimer disease and related dementias (ADRD) among patients with bladder cancer, according to a study published online May 19 in JAMA Network Open. Marc S....

Negative association of hypertension and blood pressure change with regional brain volumes stronger in men than women. Hypertension and increasing blood pressure (BP) in early adulthood are associated with lower mean regional brain volumes and poorer white matter integrity in late life, according to a study published online April 3 in JAMA Network Open.  ...

Almost everyone has trouble sleeping occasionally, but when you toss and turn often enough that it affects your health, moods and safety, your bad nights of sleeping may be elevated to the level of a sleep disorder. Sleep disorders are among the most common medical problems that health care providers see in their practices, according...

Older adults with atopic eczema are more prone to dementia. Chronic inflammation has emerged as a key predictor and mechanism in the initiation and progression of neuropathologic alterations reported in dementia patients. Atopic eczema, also known as atopic dermatitis or eczema, is a chronic skin disorder characterized by immunological dysregulation that affects 5% to 15%...

The underlying pathological mechanisms of obesity overlap with those of dementia and diabetes mellitus. Age, gender, Western diet, depression, and genetic and epigenetic factors mediate an inflammatory state, which leads to metabolic dysregulation. The development of chronic conditions can be avoided with drugs, surgical interventions, and lifestyle modifications. Dementia and diabetes mellitus (DM) are chronic...

The prevalence of risk factors for Alzheimer’s disease and related dementias varies and is highest for high blood pressure and not meeting aerobic physical activity guidelines, according to research published in the May 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. John D. Omura, M.D., from the...