Dermatology

Cost and noncost barriers more likely for sexual and gender-minority patients with chronic inflammatory skin diseases Sexual and gender-minority (SGM) patients with chronic inflammatory skin diseases (CISDs) are more likely to experience cost and noncost barriers to care, according to a study published online Sept. 27 in JAMA Dermatology. Michael R. Nock, from the Yale School...

Methotrexate treatment for refractory adult atopic dermatitis leads to changes in the cutaneous expression of IL-31 and IL-31RA, according to a recent study. Atopic dermatitis (AD) is a chronic skin disease with a complex pathophysiology. AD treatment requires inflammation reduction and skin barrier repair. Therefore, methotrexate (MTX) may serve as a treatment for patients with...

Chronic scratching increases epidermal neuronal branching and sensitivity in patients with atopic dermatitis and brachioradial pruritus, according to a recent study. Persistent and excessive scratching can worsen itch intensity, leading to an itch–scratch cycle. This repetition causes skin barrier impairment and lichenification, characterized by enhanced inflammation and neuropathy.  A study in Frontiers in Molecular Neuroscience...

A recent study found no significant association between moderate-to-severe atopic dermatitis and the incidence of non-alcoholic fatty liver disease. Atopic dermatitis (AD) is an inflammatory skin disease affecting approximately 20% of children and 2–8% of adults. Some studies have linked AD to metabolic syndrome. As metabolic syndrome is associated with non-alcoholic fatty liver disease (NAFLD),...

Topical treatment containing xyloglucan and pea protein was found to be a safe and effective steroid-sparing alternative for children with atopic dermatitis in a recent study. Atopic dermatitis (AD) is a chronic inflammatory skin condition primarily affecting children. Topical corticosteroids are the main treatment used to control skin inflammation and flare-ups in the pediatric population...

A phase III trial found that long-term dupilumab treatment demonstrated acceptable safety and sustained efficacy in children aged 6–11 years with severe atopic dermatitis. Atopic dermatitis (AD) is the most prevalent inflammatory skin disease in children. Treatment options are limited in children aged 6–11 years with severe AD inadequately controlled by topical therapies. Dupilumab has...

If you or someone you know has vitiligo, learning about available treatments like depigmentation therapy can be empowering. This therapy can offer many benefits, but like all treatments, it has its challenges. Here, we’ll explore what a recent study says about the pros and cons of depigmentation therapy. Depigmentation therapy can make a real difference...

Finding the right treatment for vitiligo can be a process. One study looked at two treatments combined with an ultraviolet light therapy called NB-UVB. Both treatments showed promise, with some areas of the body responding better than others.  Both tacrolimus 0.1% ointment and calcipotriol/betamethasone dipropionate showed promising results when combined with ultraviolet light therapy for...

If you live with atopic dermatitis, knowing about the treatment options and their effectiveness can be helpful when you discuss your treatment needs with your healthcare provider to determine the right one for you. A recent study about systemic therapies offers insight for those seeking relief. Systemic therapies don’t always provide complete relief from atopic...