Immunology

MS involves the interaction between an aberrant immune response and predisposing genetic components. Gut microbiome dysbiosis leads to neuroinflammation and the development of MS symptoms. The gut microbiome is an effective therapeutic target for the treatment of MS.  Multiple sclerosis (MS) is a neurodegenerative immune-mediated disease with a complex etiological basis. The disease is a...

In the pediatric population previously diagnosed positive for allergies, three clinical signs have high specificity and sensitivity for distinguishing airway infections and allergies: the persistence of symptoms, fever, and nasal secretions. Respiratory disorders are prevalent in the pediatric population. Additionally, there is an overlapping of symptoms of airway infections and allergies in the allergic pediatric...

This article was written by American Heart Association News There’s no vaccine for COVID-19 yet. But there are routine immunizations that people aren’t getting for a host of debilitating and potentially deadly diseases. In May, the Centers for Disease Control and Prevention reported sharp drop-offs beginning in mid-March for pediatric vaccines ordered and given. And the World Health...

Severe atopic dermatitis (AD) produces painful, itchy and unsightly patches that disrupt sleep and have been linked to increased risk of depression. Now researchers have analyzed findings from a randomized follow-up trial in adults from two previous studies (SOLO 1 and SOLO 2) and found that maintenance monotherapy with dupilumab (Dupixent, Regeneron) at 300 mg...

Atopic dermatitis (AD), a chronic, inflammatory skin disease that causes itchy, painful patches on patients has been linked to many mental health disorders, such as depression, anxiety, and suicidal tendencies. A study conducted by Jonathan Silverberg, MD, PhD, MPH, associate professor of dermatology at the George Washington University School of Medicine and Health Sciences, took...

Eczema sufferers, also known as atopic dermatitis, can attest to how difficult is to identify a suitable treatment plan. This is especially troubling because symptoms include severe itching, scaly rashes, extremely dry skin and inflammation. This battle can be even more trying for Black people with the condition. A recent study published in Annals of...

Atopic dermatitis (AD) can be complicated by infections, allergic and nonallergic comorbidities and quality of life impairments.  Understanding the severity of the disease and its comorbidities and how it affects vulnerable populations is important for clinicians who encounter AD. AD is an inflammatory, relapsing skin disease that follows a chronic, relapsing course and is characterized...

Clinicians should be aware of the differing severity and presentation of atopic dermatitis (AD) in African Americans. The frequency of atopic dermatitis is increasing, and is more common among Blacks, Asians, and Pacific Islanders. [Desai 2009] In fact, eczema is the second most frequent skin disease in African Americans. [Silverberg 2013] In the US, African...

What is Eosinophilic asthma? Eosinophilic asthma (EA) is characterized by severe, chronic disease. Approximately 10% of all cases of asthma are defined as severe, and nearly half of those with severe asthma have signs of EA. The disease typically has an onset in adulthood, with diagnosis peaking in adults aged 35-50. While most asthma results...