Neurology

Inherited ADHD seems to show unique neurological markers when compared to ADHD in those who have no familial history of the condition and healthy controls. Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent, inheritable, and heterogeneous condition. Those with a family history of ADHD are at a higher risk of developing ADHD that persists into adulthood....

ADHD has been correlated with problematic internet use, which can result in distressing self-stigma. This study analyzed this relationship while stratifying for different types of problematic internet use and their unique effects. A number of published studies have shown a link between problematic internet use and psychological stress. Youth with attention deficit hyperactivity disorder (ADHD)...

Tocilizumab is considered safe and effective for neuromyelitis optica spectrum disorder patients who do not respond to other immunosuppressants. Neuromyelitis optica spectrum disorder (NMOSD) is described as an immune-mediated inflammatory disorder that involves the B lymphocytes, astrocytes, anti-aquaporin 4 (anti-AQP4) antibodies, and inflammatory mediators in the central nervous system. This observational study, published in the...

Using resting-state fMRI results and metrics to diagnose ADHD on the basis of neural biomarkers is shown to be superior to many other neuroimaging-based approaches, while still having potential for improved accuracy in the future. Attention deficit hyperactivity disorder (ADHD) tends to be diagnosed and evaluated using behavior-based means and assessments. Although these are generally...

Cognitive impairment is common and associated with decreased quality of life and increased symptom severity in patients with neuromyelitis optica spectrum disorder. Neuromyelitis optica spectrum disorder (NMOSD) is a rare disease that can variably impact cognitive abilities, but there is little understanding of how this relates to various patient characteristics. A study published in the...

Patients with NMOSD who develop the condition at a later age are at a higher risk of experiencing severe symptoms. An inflammatory condition of the central nervous system known as neuromyelitis optica spectrum disorder (NMOSD) is characterized by recurrent episodes of optic neuritis (ON) and longitudinally widespread transverse myelitis. Patients with NMOSD who have an...

Neuromyelitis optica spectrum disorder patients have elevated plasma C5a and inflammatory cytokine levels during remission periods. Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease that affects the central nervous system (CNS), resulting in inflammation of specific brain regions, optic nerve, and spinal cord. NMSOD patients have increased complement component C5a and associated inflammatory...

Depression and initial spinal cord involvement are among the factors associated with neuropathic pain in patients diagnosed with neuromyelitis optical spectrum disorders. Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disorder with severe demyelination, especially of the optic nerve, brain, and spinal cord. Neuropathic pain is a common yet underrecognized symptom of NMOSD. The...

Inebilizumab therapy was determined to be effective for patients with prior exposure to rituximab; however, the majority of these patients experienced infections, increasing the need for vigilance. Neuromyelitis optica spectrum disorder (NMOSD) is a chronic and rare autoimmune inflammatory disorder affecting the central nervous system (CNS). NMOSD is characterized by repeated attacks of transverse myelitis,...