Neurology

The quality of life of NMOSD patients corresponds to their degree of disability and can be improved with early interventions for preventing relapse. Neuromyelitis optical spectrum disorder (NMOSD) is a rare autoimmune disorder involving the spinal cord and optic nerves. There is a consistent and strong association between the quality of life (QoL) and disability...

Therapeutic strategies for neuromyelitis optica spectrum disorder target pathogenic mechanisms of the disease and aim to restore the blood–brain barrier and enhance immune tolerance. Potential therapeutic strategies for neuromyelitis optica spectrum disorder (NMOSD) are based on targeting the B cell complement cascade system, and IL-6R. These strategies include restoration of the blood–brain barrier (BBB) and...

Findings seen for both chronic migraine and high-frequency episodic migraine patients based on pain-free state The presence or absence of nonictal allodynia can be used to identify migraine sufferers who will likely respond to galcanezumab, according to a study published online Feb. 14 in Cephalalgia. Sait Ashina, M.D., from the Beth Israel Deaconess Medical Center...

Increased odds of 30-day mortality ranges from 2.46 to 1.23 for nontraumatic coma and stroke. Neighborhood socioeconomic status (SES) is associated with 30-day mortality for common neurologic conditions, according to a study published online Feb. 15 in Neurology. Jay B. Lusk, from the Duke University School of Medicine in Durham, North Carolina, and colleagues examined the...

Emotional dysregulation may function as a fourth core symptom of ADHD, and it has many wide-ranging negative effects in adults. Although the symptoms and effects of ADHD vary, the condition tends to have lasting effects on the social, academic, and professional lives of those affected. ADHD first appears in childhood and continues to affect between...

The effects of environmental stressors on cognitive conditions are complex, and this article provides insights into how and why these stressors continue to affect certain communities more than others. The combined effects of environmental toxicants and social stressor exposures have been recognized by past research as important public health problems that can likely contribute to...

You walk into the room and see their face. They smile at you and look into your eyes. And just like that, your heart drops to your feet and you can’t speak. At least, not coherently. What’s happening to your brain? Falling in love may make you feel like it has turned to mush, but...

A genetic score may be able to identify higher stroke risk – but only for people living in the most privileged neighborhoods, according to new research that highlights inequities related to wealth and health. Researchers looked at acute ischemic stroke, the most common type of stroke. It is caused by a clot blocking blood flow...

Sleeping less than seven hours per night and self-reported low sleep quality during adolescence associated with risk for developing MS Insufficient sleep and low sleep quality during adolescence may increase the risk for subsequently developing multiple sclerosis, according to a study published online Jan. 23 in the Journal of Neurology, Neurosurgery & Psychiatry. Torbjörn Åkerstedt,...