Oncology

Recent advancements in CAR-T cell therapies have shown encouraging results for patients with relapsed/refractory multiple myeloma. While the promise is high, barriers like manufacturing availability and socioeconomic disparities pose challenges to making these treatments widely accessible. Two CAR-T cell therapies, idecabtagene vicleucel and ciltacabtagene autoleucel, have shown positive outcomes in patients with poor prognosis. Barriers...

A systematic review reveals disparities in the incidence, treatment, and outcomes of Hispanic Americans with multiple myeloma. These disparities may indicate an urgent need for structural solutions to ensure equitable healthcare access for this demographic. Hispanic Americans face health disparities in multiple myeloma, exhibiting worse clinical outcomes than other ethnic groups. The incidence of multiple...

This analysis explores the intricate relationship between continuity of care and treatment outcomes in advanced prostate cancer patients within the Medicare system. Specifically, it sheds light on the impact of racial disparities on these healthcare dynamics, offering fresh insights for improved patient care strategies. Higher continuity of care is linked to reduced emergency room visits,...

A recent large-scale study investigated the use of comprehensive genomic profiling and treatment patterns across ancestries to determine their impact on ancestral disparities in advanced prostate cancer. The research provides crucial insights into the genomic landscape and clinical treatment patterns in diverse ancestries, focusing on African and European backgrounds. Advanced prostate cancer genomics and treatment...

In light of persistent racial disparities in prostate cancer care, a recent review discusses current understanding and future directions towards a more equitable healthcare approach. Highlighting the importance of social determinants of health, the study points to potential strategies for improving the standard of care for marginalized communities. Disparities in prostate cancer care are well...

This review reveals significant associations between obesity and liver, prostate, breast, and colorectal cancers. Obesity has become a major public health issue over the last few decades. It has been associated with multiple metabolic syndromes and an increased risk of malignancies. Moreover, growing evidence shows that weight loss may lower the risk of developing cancer....

The 5Ts for Teach-Back method of health education can improve compliance with oral nutritional supplements in post-discharge patients after gastric cancer surgery. Surgery for gastric cancer results in metabolic changes and absorption disorders, leading to worsening nutritional status after discharge. Oral nutritional supplements (ONS) are recommended for malnutrition after tumor surgery; however, studies show poor...

Greater effect seen for patients aged 70 years and older at time of bacillus Calmette-Guerin vaccination. The bacillus Calmette-Guerin (BCG) vaccine is associated with a significantly lower rate and risk for Alzheimer disease and related dementias (ADRD) among patients with bladder cancer, according to a study published online May 19 in JAMA Network Open. Marc S....

Cladosporium sp. was more commonly found in early-onset CRC, while Pseudomonas luteola, Ralstonia sp., Moraxella osloensis occurred more often in late-onset CRC. The microbiome (MB) of patients with colorectal cancer (CRC) varies between those diagnosed with early- or late-onset disease, according to a study presented at the annual meeting of the American Society of Clinical Oncology, held from June...