Oncology

Higher levels of a certain type of immune cell may explain why immunotherapy for prostate cancer is more effective in Black men than in white men, researchers say. The finding could lead to immunotherapy-based precision treatment for localized aggressive and advanced prostate cancer in all races. For the study, the researchers analyzed 1,300 prostate tumor...

FRIDAY, July 10, 2020 — U.S. government-funded clinical trials for new cancer treatments have more Black participants than those run by drug companies, but Blacks are still underrepresented in cancer studies, researchers say. The SWOG Cancer Research Network team analyzed data from 358 clinical trials — 85 drug industry trials and 273 SWOG trials. They...

TUESDAY, Oct. 13, 2020 — More than half of patients offered participation in cancer clinical trials are willing to participate, according to a study published online Oct. 6 in the Journal of the National Cancer Institute to coincide with the ASCO Quality Care Symposium, held virtually from Oct. 9 to 10. Joseph M. Unger, Ph.D., from...

MONDAY, Dec. 7, 2020 — High blood pressure affects Black adults in the U.S. more than any other group. But studies exploring its impact on them remain scant, an analysis of clinical trials over the past decade shows. The analysis, published Monday in the Journal of the American Heart Association, found that of the 956...

Glioblastoma (GBM) is the most common malignant brain tumor originating in the brain. This study, published in CNS Oncology, analyzes disparities in GBM clinical trials. Due to the prevalence and severity of GBM, gaining an accurate understanding of how the disease impacts the general population is essential. Radiation plus concurrent adjuvant temozolomide remains the standard...

Recruitment and enrollment of diverse participants representative of the general population are essential to gain meaningful insight into novel drug therapies. Oncological studies have been previously noted as lacking gender balance, which can result in skewed clinical trial results. This study, published in the Journal of Clinical Oncology, focuses on drug registration trials in particular,...

TUESDAY, Oct. 13, 2020 — There are considerable racial- and ethnicity-based cancer health disparities in the United States, according to a report published online Sept. 16 by the American Association for Cancer Research. John D. Carpten, Ph.D., from the University of Southern California in Los Angeles, and colleagues discussed cancer health disparities in the U.S....

The risk of prostate cancer is 75% higher in Black patients compared to white patients. Despite worse outcomes, Black patients are still underrepresented as research participants. A recent study not only found new genetic markets of prostate cancer risk but also identified a risk profile that can be applied across populations, emphasizing the value of...

Pooled relative risk of 0.988 for each increment of one cup of coffee per day revealed in meta-analysis of cohort studies Increased coffee consumption is associated with a reduced risk for prostate cancer, according to a review and meta-analysis published online Jan. 11 in BMJ Open. Xiaonan Chen, from Shengjing Hospital of China Medical University, and...