Clinical Trials

Multiple Myeloma Status Quo Over 30,000 Americans are diagnosed with multiple myeloma each year. And more than 12,500 Americans pass away due to multiple myeloma annually. Multiple myeloma is a cancer of plasma cells. With multiple myeloma, the bone marrow consists of excess plasma cells associated with monoclonal protein in the blood and/or urine. Clinical...

In this MD Newsline exclusive interview with health education and wellness physician Dr. Ilan Shapiro, we discuss how to improve the inclusion of Latino participants and Latino leadership in clinical trials. MD Newsline: How do you think we can increase the recruitment and enrollment of Latinos in clinical trials to help improve health outcomes for...

Overall, progression-free, and cancer-specific survival worse for participants from areas with highest socioeconomic deprivation. High area-level socioeconomic deprivation is associated with worse survival for patients with cancer enrolled in clinical trials, according to a study published online March 17 in the Journal of Clinical Oncology. Joseph M. Unger, Ph.D., from the Fred Hutchinson Cancer Research...

Cancer patients most likely to sign up for clinical trials during their treatment include people of color, those with higher incomes and those who are younger, a new study finds. “This study informs our understanding of who is participating in cancer clinical trials,” said study author Dr. Lincoln Sheets, an assistant research professor at the...

The globalization of cancer clinical trials is associated with a widening racial disparity in enrollment, according to a study published online March 8 in Cancer. Serena Tharakan, from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues analyzed race and accrual location data for all U.S. Food and Drug Administration-approved...

Prostate cancer in the transgender female population is an area lacking research, adequate clinical trials, and resources for medical professionals. This deficit of knowledge and difficulty accessing services puts the transgender female population at a disadvantage when it comes to being diagnosed with and treated for prostate cancer. To date, there have only been ten...

Dealing with diversity and adequate representation in Alzheimer’s Disease clinical trials is especially pressing due to the large number of individuals with this disease and the very high failure rate (99.6%) of new drugs. This literature review, published in the Journal of Alzheimer’s Disease, analyzes the racial and sex-based disparities in Alzheimer’s clinical trials over...

Under-enrollment in clinical trials can significantly impact the development of appropriate treatment options, reducing the validity of researched outcomes. In many cases, it can also result in the early termination of the research studies themselves. This study, published in the Journal of Neuro-Oncology, analyzes the impact of race/ethnicity and socioeconomic status on enrollment rates in...

Randomized clinical trials are an essential component of the development and proper deployment of novel therapies. However, there are many disparities in access to and participation in clinical trials throughout the United States. Moreover, the COVID-19 pandemic has resulted in large-scale destabilization, which has extended to clinical trials. This article, published in Ethnicity & Disease,...