fbpx Skip to main content

Age-related macular degeneration (AMD) is becoming more prevalent due to the steady increase in human life expectancy. The visual impairment caused by this disease wreaks havoc on patient quality of life by limiting patient self-sufficiency. Thus, it is crucial to determine what factors contribute to disease progression and prevention.

In this literature review, data were gathered from randomized controlled trials, prospective cohort studies, and case-control studies to analyze patient nutritional intake, specifically carbohydrates, and their association with age-related vision loss. Patient gene variants were also evaluated to help determine how gene-diet interactions may contribute.

The Melbourne Collaborative Cohort study identified six dietary patterns associated with AMD. One dietary pattern consisting of grains, fish, boiled or steamed chicken, vegetables, and nuts protected against late AMD. There was no significant association between early or late AMD and fruits and vegetables.

In the Rotterdam Eye Study, a prospective population cohort, nine dietary patterns were defined, and the association with AMD patients was analyzed. An AMD-protective dietary pattern was found to consist of vegetables (200g/day or more), fruits (2x/day), and fish (2x/week). Other nutritional habits that included vegetables, fruits, and fish in conjunction with eggs, poultry, meats, and potatoes did not reach statistical significance.

Results varied for the healthiest diet for the prevention of AMD. Yet, several conclusions can be made from this data. The prudent dietary pattern, the Mediterranean diet, and the Healthy Eating Index all protect against late AMD, which could later progress to wet AMD.

A call to action is made for further research to understand why and how a patient’s diet contributes to the risk of AMD. More reliable methods of study must also be implemented [1].

You May Also Like::  Dr. Rishi Singh: Risk Factors for Wet AMD


[1] Francisco, S. G., Smith, K. M., Aragonès, G., Whitcomb, E. A., Weinberg, J., Wang, X., Bejarano, E., Taylor, A., & Rowan, S. (2020). Dietary Patterns, Carbohydrates, and Age-Related Eye Diseases. Nutrients, 12(9), 2862. https://doi.org/10.3390/nu12092862

“Keeping up with the indications and adverse reactions to immune checkpoint inhibitors can be a full-time job. Cutaneous side effects occur in up to 45% of patients treated with ipilimumab and 34% of patients treated with nivolumab and pembrolizumab.” https://bit.ly/3FGtxtd

.@spfnomt: This month’s #DermWorld article “Estate planning 101” is especially important for young physicians to read. The long, all-consuming years between adolescence and physicianhood can become a blur...https://bit.ly/3FxOtCv

That’s a wrap #AAD2023! 5 days of soaking up knowledge from dermatologists on topics such as hidradenitis, melasma, & dietary triggers of common dermatoses.

I LOVED the #womenshealth focused sessions on vulvar dermatoses and pregnancy medication safety.


New approach uses microbiome to treat skin disease by repairing the injured microbiome that allowed inflammation to flare up in the first place, rather than reducing the inflammation after the fact. https://bit.ly/3Jt6H9v

Load More