Sickle Cell Disease
Weill Cornell Medicine's Dr. Cheryl Mensah Discusses Covid-19's Effect on Sickle Cell Disease and More
In 2019 there was much buzz and excitement surrounding sickle cell disease and the upcoming breakthroughs in store for patients. With the onset of Covid-19 came a shift in medical practices leaving healthcare providers and patients alike wondering how their treatments and new therapies would be affected. MDNewsline sat down with Dr. Cheryl Mensah, a...
Endurance Exercise May Offer Vascular Benefit in Sickle Cell Disease
Increases in capillary density, functional exchange surface seen in microvasculature of skeletal muscle (HealthDay News) — Endurance exercise training may improve skeletal muscle microvasculature in patients with sickle cell disease (SCD), according to a study published online Nov. 19 in Blood. Angèle N. Merlet, Ph.D., from the Universitè de Lyon in France, and colleagues examined the...
Sickle Cell Disease Treatment Options
Sickle cell disease (SCD) is the most common genetic disease affecting 100,000 people in the U.S. According to the CDC 1 out of 365 African Americans and 1 out of 16,300 Hispanic- Americans have sickle cell disease. The majority of SCD patients are medicaid beneficiaries (less than 70% of doctors in the U.S. accept new...
FDA Approves Oxbryta, Second Sickle Cell Drug Approval in 10 Days
On Monday November 25 the U.S. Food and Drug Administration granted accelerated approval to Oxbryta (voxelotor) for the treatment of sickle cell disease (SCD) in adults and pediatric patients 12 years of age and older. “Today’s approval provides additional hope to the 100,000 people in the U.S., and the more than 20 million globally, who...
Dr. Edward Ivy: Improving Access to Care in Sickle Cell Disease
I have lived with sickle cell disease for 48 years. The toll it takes goes far beyond pain – it has impacted me emotionally, economically, and psychosocially. I missed childhood activities because I was too sick or tired. I missed school days and worked harder to catch up on missed assignments. I learned to live...
FDA Approves First Targeted Therapy to Treat Patients With Painful Complication of Sickle Cell Disease
On November 15 the U.S. Food and Drug Administration approved Adakveo (crizanlizumab-tmca), a treatment to reduce the frequency of vaso-occlusive crisis – a common and painful complication of sickle cell disease that occurs when blood circulation is obstructed by sickled red blood cells – for patients age 16 years and older. “Hope has never been...
Sickle Cell & PTSD Predictor in Healthcare disparity
Posttraumatic Stress Disorder (PTSD) is a psychiatric disorder that occurs in people who have experienced a personal assault or who have witnessed a traumatic event. The exposure to an upsetting traumatic event can be indirect rather than first-hand such as of learning of a violent death of a close family member. In Sickle Cell Anemia...
Gene Therapy, Next Up For Sickle Cell Disease?
Sickle Cell Disease has been at the forefront of inherited disorders that have been studied to determine the exact gene mutation. When Geneticists discovered the mutation on the Hemoglobin-Beta gene on Chromosome 11 causes Sickle Cell Disease, this information was mostly used to counsel persons who carry the trait regarding the need for genetic testing...
Global Policy: What You Need To Know About Sickle Cell Disease
Sickle Cell Disease (SCD) affects persons whose ancestors come from sub-Saharan Africa; Spanish-speaking regions in the Western Hemisphere (South America, Central American and the Caribbean); Mediterranean countries such as Turkey, Greece, and Italy; India and Saudi Arabia. In the United States, 1 in 13 African American babies is born with Sickle Cell Trait (SCT) wherein...
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