Neurology

Limited studies have been conducted on the long-term course of neuromyelitis optica spectrum disorder (NMOSD). However, one study sought to examine the effect of sociodemographic and illness-related factors on disease progression five years after the onset of illness. Neuromyelitis optica spectrum disorder (NMOSD) is a progressive, autoimmune disease that attacks the central nervous system, causing...

Patients with neuromyelitis optica spectrum disorder (NMOSD) may be prone to experiencing worse COVID-19 outcomes. As an autoimmune disease, NMOSD is detrimental to the optic nerve and central nervous system. Patients with NMOSD may experience disease onset at a later age, have comorbidities, and often be treated with immunosuppressive therapy, such as rituximab, azathioprine, mycophenolate...

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune condition that affects the central nervous system and can be particularly dangerous in pregnant women. The effects of NMOSD can be harmful to both the mother and the fetus, with an increased risk of relapse and disability. While immunosuppressive therapy is the cornerstone of treatment for pregnant...

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disorder that manifests as inflammation of the optic nerves and central nervous system. Cases of NMOSD can typically be diagnosed with an antibody test for myelin oligodendrocyte glycoprotein (MOG) or aquaporin-4 (AQP4). Most cases are AQP4 antibody–seropositive NMOSD, with a mean age of onset of 40 years...

The prevalence of neuromyelitis optica spectrum disorder (NMOSD) is higher in racial minority groups than in white populations, with varying disease manifestations and severity. Moreover, limited data suggest that NMOSD has an earlier age of onset and tends to have worse outcomes in racial minorities. This retrospective study, published in Neurology, sought to address doubts and...

Incident conditions that may be attributable to COVID-19 are common among adult COVID-19 survivors, according to research published in the May 24 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Lara Bull-Otterson, Ph.D., from the CDC COVID-19 Emergency Response Team, and colleagues used electronic health record data...

The prevalence of risk factors for Alzheimer’s disease and related dementias varies and is highest for high blood pressure and not meeting aerobic physical activity guidelines, according to research published in the May 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. John D. Omura, M.D., from the...

How does spinal muscular atrophy (SMA) impact the mental health of children and young adults? A recent cross-sectional study published in the Orphanet Journal of Rare Diseases sought to answer this question and determine the prevalence and possible contributing factors of anxiety and depression in school-age patients with SMA. The study included over 150 participants ages 8...

Spinal muscular atrophy (SMA) was added to the U.S. Recommended Uniform Screening Panel (RUSP) in 2018. This study, published in the International Journal of Neonatal Screening, examined the 34 fully implemented spinal muscular atrophy (SMA) newborn screening (NBS) programs in the U.S. and several programs on the path to implementation as of June 2021.  Data were gathered on the...