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Various factors influencing the health-related quality of life of non-Hodgkin lymphoma survivors were revealed in a recent study. The study results highlight the links between socio-demographics, clinical attributes, and psychological conditions. This research provides a comprehensive perspective, potentially influencing tailored interventions in the future. Non-Hodgkin lymphoma survivors show distinct health-related quality of life (HRQoL) challenges....

Nivolumab monotherapy produced a modest response rate in patients with nccRCC, with higher response rates observed in patients with higher PD-L1 expression. In 2015, the FDA approved nivolumab monotherapy for treating clear cell renal cell carcinoma (ccRCC) patients who are resistant to vascular endothelial growth factor receptor tyrosine kinase inhibitors. A trial examined the effectiveness...

Bimekizumab demonstrates overall greater efficacy than guselkumab in psoriatic arthritis patients at 52 weeks, according to an analysis of data from several trials. Approximately 30% of psoriasis patients develop psoriatic arthritis (PsA). Recent Phase 3 trials have demonstrated the efficacy and safety of bimekizumab (an interleukin-17F and IL-17A inhibitor) and guselkumab (an interleukin-23 inhibitor) in...

THURSDAY, Feb. 25, 2021 (HealthDay News) — A machine learning-based model has been developed and validated for predicting malignancy in multiple pulmonary nodules (MPNs), according to a study published online Feb. 24 in Clinical Cancer Research. Kezhong Chen, M.D., from the Peking University People’s Hospital in Beijing, and colleagues developed and validated a machine learning-based...

Surgical approach is not associated with intermediate-term decision regret following radical prostatectomy, according to a study published in the March issue of The Journal of Urology. Martin Baunacke, M.D., from Technische Universität Dresden in Germany, and colleagues evaluated intermediate-term decision regret after open (532 patients) and robot-assisted (404 patients) radical prostatectomy (2008 to 2013). The analysis...

Patients with skin of color (SOC) face disproportionately high rates of morbidity and mortality from melanoma. Increasing the awareness of disparities in melanoma recognition and improving diagnostic strategies are key to improving the outcomes of melanoma. Melanoma is a relatively common skin cancer that affects all groups of people in the United States. However, the...

Lesbian, gay, and bisexual (LGB) adults differ from heterosexual adults on several health indicators, according to a study published in the National Health Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention. Kevin C. Heslin, Ph.D., and Johanna M. Alfier, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland,...

Multiple myeloma is a serious health issue. It is a form of cancer that develops within bone marrow due to genetic mutations.  So, since this cancer develops from genetic mutations, does that mean it is hereditary? This article will explore the answer to this question while also looking at other risk factors.  What Is Multiple...

Tumor mutational burden (TMB) refers to the total number of non-inherited mutations found in the DNA of cancer cells and can help determine the best course of treatment. This retrospective study, published in Future Oncology, focuses on the use of tumor mutational burden testing in pan-tumor populations. So far, there is limited real-world information regarding...