Wet AMD

Many barriers prevent patients with wet age-related macular degeneration (AMD) from adhering to their appointments. COVID-19 was a major barrier for many patients who did not want to risk leaving home for eye screening or follow-up appointments due to fear of catching the virus. Transportation is an especially challenging barrier for patients with wet AMD....

Of the two forms of age-related macular degeneration (AMD), non-neovascular (dry) AMD and neovascular (wet) AMD, 90% of all AMD cases are classified as dry, meaning the macula’s light-sensitive cells slowly deteriorate. Cases of wet AMD are less common (10%) but more severe. Wet AMD is advanced AMD that can cause legal blindness in patients,...

Anti-vascular endothelial growth factor therapy, or anti-VEGF therapy, has become one of the most useful and effective therapies for wet age-related macular degeneration (AMD). This retrospective cohort study focuses on racial/ethnic differences in anti-VEGF intravitreal injection treatment. The 104,430 patients studied were commercially insured and had wet AMD, among other conditions. Main outcomes included receiving...

Choroidal neovascularization (CNV) refers to the growth of blood vessels that break into the subretinal pigment epithelium. It is a major cause of vision loss and is associated with wet age-related macular degeneration (AMD). This study sought to analyze novel biomarkers and gene expression signatures of AMD and focuses on the EFEMP1 gene. The researchers...

Convolutional neural networks (CNN) are a type of deep learning neural network that is most often used to evaluate visual imagery. Detection of Apoptosing Retinal Cells (DARC) is a technique that uses laser ophthalmoscopy to create images of the retina. This study focuses on using a CNN DARC algorithm to predict subretinal fluid formation in...

Low vision — poor eyesight that can’t be corrected by glasses, contact lenses, surgery or medication — afflicts more than 2 million Americans, according to the National Eye Institute (NEI). But this is a conservative estimate. Some 14 million Americans suffer from visual impairment if you include those with eye problems that hamper the performance...

It is crucial that patients with age-related macular degeneration (AMD) are diagnosed early and receive continuous medical care. If not managed adequately, the outcome for patients with AMD is likely poor, and the disease may progress to wet AMD. Researchers sought to determine what socioeconomic barriers may be to blame for patients who are not...

Previous research has shown that wet and dry age-related macular degeneration (AMD) are most prevalent in Caucasian Americans. Asian Americans experience the next highest prevalence rates, followed by Hispanic Americans, and lastly, African Americans. The characteristics and progression of disease also vary based on patient race and ethnicity. Researchers sought to characterize the progression of...

Age-related macular degeneration (AMD) is becoming more prevalent due to the steady increase in human life expectancy. The visual impairment caused by this disease wreaks havoc on patient quality of life by limiting patient self-sufficiency. Thus, it is crucial to determine what factors contribute to disease progression and prevention. In this literature review, data were...